Immunol Med Micro ’01: Orally consumed probiotics help urogenital infection


Reid G, Bruce AW, Fraser N. Oral probiotics can resolve urogenital infections. FEMS Immunol Med Microbiol 2001;30:49-52.

We report the first clinical evidence that probiotic lactobacilli can be delivered to the vagina following oral intake.

In 10 women with a history of recurrent yeast vaginitis, bacterial vaginosis (BV) and urinary tract infections, strains Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14 suspended in skim milk and given twice daily for 14 days, were recovered from the vagina and identified by morphology and molecular typing within 1 week of commencement of therapy.

In six cases of asymptomatic BV or intermediate BV (based upon Nugent scoring) was resolved within 1 week of therapy.

PMID: 11172991